Portfolio

Therapeutics:

Actrx - T-cell adoptive immunotherapies for cancer, infectious diseases, and immune disorders. (Carl June)

Anosos Biotherapeutics - Developing next generation complement modulators, aimed at diseases with a significant inflammatory component. (John Lambris)

Axonia Medical - Proprietary technology platform allowing stretch growth of axon bundles for use as fully functional grafts to address peripheral and CNS neuropathies. (Douglas Smith)

Butterfly Biosciences - Novel RNA therapeutic platform. (Robert Wilson)

Cetazam Therapeutics - Cerebral vascular spasm treatments using Salvia divinorum. (RenYu Liu)

Cloverleaf Therapeutics - tRNA targeted therapeutics for treating cancer and other diseases. (Xiaolu Yang)

DermoBiotech - Human hair follicle stem cell (hHFSC) platform for dermatology-focused regenerative medicine applications. (George Xu)

Directamab - Targeted personalized antibody diagnostic/therapeutic platform. (Nathalie Scholler)

Invidisyn - Developing small-molecule inhibitors of viral nucleic acid synthesis with potent antiviral activity. (Robert Ricciardi)

Key Cytotherapeutics - Developing novel dendritic cell cancer vaccines. (Brian Czerniecki)

Novapeutics - Men1 pathway modulators for diabetes and cancer treatments. (Xianxin Hua)

Quern Therapeutics - Novel reversal agent for Heparin-induced thrombocytopenia (HIT). (Bruce Sachais)

RelGene - cRel inhibitors for multiple sclerosis and other inflammatory diseases. (Youhai Chen)

Vetagenics - Generating canine single chain fragment variable antibody libraries for targeting tumor-associated antigens in canines. (Nicola Mason)

Xymedix - Novel therapeutic antibodies against inflammatory and autoimmune diseases. (Wenchao Song)

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Diagnostics:

APlus Radiopharmaceuticals - Molecular imaging agents for early diagnosis of cancers. (Hank Kung)

Cerebromarkers - Developing biomarkers for diagnosis and improved treatment of traumatic brain injury. (Robert Siman)

Cognizance Biomarkers - Biomarkers and potential treatments for epilepsy. (John Pollard)

CytoVas - Novel high-throughput, high-content flow cytometry test for patients at high risk for cardiovascular events. (Emile Mohler)

FibRHO Diagnostics - T1p MR imaging for the non-invasive staging of hepatic fibrosis. (Rebecca Wells)

MicropathID Diagnostics - A pathogen array for the identification of etiological agents associated with disease states. (Erle Robertson)

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Devices:

Annulon - Prototyping and testing a catheter-based percutaneous valve replacement technology. (Joseph Gorman and Robert Gorman)

Cerebid Technologies - Color changing blast injury dosimeter. (Douglas Smith)

Innofect - Dermal disinfection products for the medical, research and consumer marketplaces. (Paul Axelsen)

Mem Technologies - miRNA quantification platform using nanopores for disease detection and drug discovery. (Marija Drndic)

Oxygense - Developing an optical method and instrument for tissue oxygen measurement and imaging to diagnose and monitor clinically important pathologies, including diabetic retinopathy. (David Wilson)

TIPER Technologies - Precisely controlled and highly efficient cell conversion platform that allows for the creating of custom cell populations (e.g. pluripotent progenitor cells). (James Eberwine)

Virtuscan - Interactive MRI training and simulation software for clinicians and researchers. (Jeremy Magland)

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Materials:

Cellulosic Biotherapeutics - Developing novel polysaccharide hydrogels for soft tissue regeneration, including aesthetic medicine applications. (Steven Nicoll)

Fibradigm Therapeutics - Construction of implant materials that mimic the mechanical properties of replaced tissue. (Matthew Fisher)

Graphene Frontiers - Synthesis technologies to produce high quality large scale graphene thin films. (Charles Johnson)

GSL BioLogix - Multi-functional polymers that impart the surface of medical devices with biocompatibility and antibacterial properties. (Russell Composto and David Eckmann)

Myostratum - Developing the use and application of tissue expanding filler materials to promote remodeling of cardiac tissue after infarction. (Robert Gorman and Joseph Gorman)

Nelum Sciences - Surface coatings for a wide range of applications, including superhydrophobicity, superhydrophilicity, highly oleophobicity, anti-fouling and dry adhesion. (Shu Yang)

United Catalyst - Novel imprinted organosilicates used to generate ethanol from cellulose. (Stephen Roth)

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Healthcare IT:

Antray - A software system for tracking usage and experimental data from user-operated equipment. (Wade Rogers)

RightCare Solutions - A post-acute referral decision support system for hospitals and medical centers. (Kathryn Bowles)

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